SLC39A12

SLC39A12
Identifiers
Aliases	SLC39A12, LZT-Hs8, ZIP-12, bA570F3.1, solute carrier family 39 member 12
External IDs	MGI: 2139274 HomoloGene: 17654 GeneCards: SLC39A12
Gene ontology Molecular function • metal ion transmembrane transporter activity • zinc ion transmembrane transporter activity Cellular component • perinuclear region of cytoplasm • integral component of membrane • extracellular vesicle • plasma membrane • membrane • integral component of plasma membrane Biological process • metal ion transport • zinc II ion transport • ion transport • regulation of neuron projection development • regulation of microtubule polymerization • transmembrane transport • cellular zinc ion homeostasis • signal transduction • zinc II ion transmembrane import • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	221074	277468
Ensembl	ENSG00000148482	ENSMUSG00000036949
UniProt	Q504Y0	Q5FWH7
RefSeq (mRNA)	NM_152725 NM_001145195 NM_001282733 NM_001282734	NM_001012305
RefSeq (protein)	NP_001138667 NP_001269662 NP_001269663 NP_689938	NP_001012305
Location (UCSC)	Chr 10: 17.95 – 18.04 Mb	Chr 2: 14.39 – 14.49 Mb
PubMed search

221074

277468

ENSG00000148482

ENSMUSG00000036949

Q504Y0

Q5FWH7

NM_152725
NM_001145195
NM_001282733
NM_001282734

NM_001012305

NP_001138667
NP_001269662
NP_001269663
NP_689938

NP_001012305

Solute carrier family 39 member 12 is a protein that in humans is encoded by the SLC39A12 gene.

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).

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