SLC39A1

SLC39A1
Identifiers
Aliases	SLC39A1, ZIP1, ZIRTL, solute carrier family 39 member 1
External IDs	MGI: 1353474 HomoloGene: 40906 GeneCards: SLC39A1
Gene location (Human) Chr. Chromosome 1 (human) Band 1q21.3 Start 153,959,099 bp End 153,968,184 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band n/a Start 90,248,172 bp End 90,253,612 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • receptor binding • metal ion transmembrane transporter activity • inorganic cation transmembrane transporter activity • zinc ion transmembrane transporter activity Cellular component • integral component of membrane • plasma • endoplasmic reticulum membrane • membrane • endoplasmic reticulum Biological process • embryonic cranial skeleton morphogenesis • metal ion transport • zinc II ion transmembrane transport • cation transport • zinc II ion transport • in utero embryonic development • ion transport • limb development • transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	27173	30791
Ensembl	ENSG00000143570	ENSMUSG00000052310
UniProt	Q9NY26	Q9QZ03
RefSeq (mRNA)	NM_014437 NM_001271957 NM_001271958 NM_001271959 NM_001271960 NM_001271961	NM_013901
RefSeq (protein)	NP_001258886 NP_001258887 NP_001258888 NP_001258889 NP_001258890 NP_055252	NP_038929
Location (UCSC)	Chr 1: 153.96 – 153.97 Mb	Chr 1: 90.25 – 90.25 Mb
PubMed search

27173

30791

ENSG00000143570

ENSMUSG00000052310

Q9NY26

Q9QZ03

NM_001271961

NM_013901

NP_055252

NP_038929

Zinc transporter ZIP1 is a protein that in humans is encoded by the SLC39A1 gene.

The protein ZIP1 is responsible for the active transport of zinc into prostate cells. In many prostate cancers SLC39A1 is silenced causing prostate cancer cells to be low in zinc.

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Wikipedia