SLC38A1

SLC38A1
Identifiers
Aliases	SLC38A1, ATA1, NAT2, SAT1, SNAT1, solute carrier family 38 member 1
External IDs	MGI: 2145895 HomoloGene: 12745 GeneCards: SLC38A1
Gene ontology Molecular function • neutral amino acid transmembrane transporter activity • protein binding • sodium:amino acid symporter activity • symporter activity • L-amino acid transmembrane transporter activity • amino acid transmembrane transporter activity Cellular component • integral component of membrane • membrane • plasma membrane • integral component of plasma membrane • extracellular exosome Biological process • sodium ion transport • neurotransmitter uptake • amino acid transport • neutral amino acid transport • ion transport • L-alpha-amino acid transmembrane transport • amino acid transmembrane transport • L-amino acid transport • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	81539	105727
Ensembl	ENSG00000111371	ENSMUSG00000023169
UniProt	Q9H2H9	Q8K2P7
RefSeq (mRNA)	NM_001077484 NM_001278387 NM_001278388 NM_001278389 NM_001278390 NM_030674	NM_001166456 NM_001166458 NM_134086
RefSeq (protein)	NP_001070952 NP_001265316 NP_001265317 NP_001265318 NP_001265319 NP_109599	NP_001159928 NP_001159930 NP_598847
Location (UCSC)	Chr 12: 46.18 – 46.27 Mb	Chr 15: 96.57 – 96.64 Mb
PubMed search

81539

105727

ENSG00000111371

ENSMUSG00000023169

Q9H2H9

Q8K2P7

NM_030674

NM_001166456
NM_001166458
NM_134086

NP_109599

NP_001159928
NP_001159930
NP_598847

Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene.

Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001).[supplied by OMIM]

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Wikipedia