SLC30A1

SLC30A1
Identifiers
Aliases	SLC30A1, ZNT1, ZRC1, solute carrier family 30 member 1
External IDs	MGI: 1345281 HomoloGene: 6681 GeneCards: SLC30A1
Gene location (Human) Chr. Chromosome 1 (human) Band n/a Start 211,571,568 bp End 211,578,742 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band n/a Start 191,906,767 bp End 191,913,247 bp
Gene ontology Molecular function • calcium channel inhibitor activity • cation transmembrane transporter activity • protein binding • zinc ion transmembrane transporter activity Cellular component • cytoplasm • integral component of membrane • Golgi apparatus • nuclear membrane • membrane • T-tubule • plasma • endoplasmic reticulum Biological process • negative regulation of neurotransmitter secretion • calcium ion import • zinc II ion transport • cellular calcium ion homeostasis • response to zinc ion • cation transport • in utero embryonic development • ion transport • negative regulation of calcium ion import • detoxification of cadmium ion • negative regulation of zinc ion transmembrane import • zinc II ion transmembrane transport • cellular zinc ion homeostasis • cadmium ion transmembrane transport • regulation of sequestering of zinc ion • transmembrane transport • regulation of molecular function • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7779	22782
Ensembl	ENSG00000170385	ENSMUSG00000037434
UniProt	Q9Y6M5	Q60738
RefSeq (mRNA)	NM_021194	NM_009579
RefSeq (protein)	NP_067017	NP_033605
Location (UCSC)	Chr 1: 211.57 – 211.58 Mb	Chr 1: 191.91 – 191.91 Mb
PubMed search

7779

22782

ENSG00000170385

ENSMUSG00000037434

Q9Y6M5

Q60738

NM_021194

NM_009579

NP_067017

NP_033605

Solute carrier family 30 (zinc transporter), member 1 is a protein which in humans is encoded by the SLC30A1 gene.

SLC30A1 modulates zinc permeation through the L-type calcium channel. SLC30A1 downregulates not only Zn⁺⁺ influx, but also Ca⁺⁺ influx, thereby protecting cells from the effects of excessive cation permeation.

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Wikipedia