SIRPG

SIRPG
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2JJW, 4I2X
Identifiers
Aliases	SIRPG, CD172g, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1, signal regulatory protein gamma
External IDs	HomoloGene: 56809 GeneCards: SIRPG
Gene ontology Molecular function • protein binding Cellular component • integral component of membrane • plasma membrane • membrane • intracellular Biological process • cell-cell signaling • cell adhesion • intracellular signal transduction • positive regulation of T cell activation • leukocyte migration • positive regulation of cell proliferation • negative regulation of cell proliferation • positive regulation of cell-cell adhesion Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55423	n/a
Ensembl	ENSG00000089012	n/a
UniProt	Q9P1W8	n/a
RefSeq (mRNA)	NM_001039508 NM_018556 NM_080816	n/a
RefSeq (protein)	NP_001034597 NP_061026 NP_543006	n/a
Location (UCSC)	Chr 20: 1.63 – 1.66 Mb	n/a
PubMed search		n/a

2JJW, 4I2X

55423

n/a

ENSG00000089012

n/a

Q9P1W8

n/a

NM_001039508
NM_018556
NM_080816

n/a

NP_001034597
NP_061026
NP_543006

n/a

Signal-regulatory protein gamma is a protein that in humans is encoded by the SIRPG gene. SIRPG has also recently been designated CD172G (cluster of differentiation 172G).

The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

...
Wikipedia