SH3BP2

SH3-domain binding protein 2
Identifiers
Symbol	SH3BP2
Entrez	6452
HUGO	10825
OMIM	602104
RefSeq	NM_003023
UniProt	P78314
Other data
Locus	Chr. 4 p16.3

SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. SH3BP2 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. It binds to phosphatidylinositols linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. It is also associated with cherubism.

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