SGK3

Identifiers

SGK3, CISK, SGK2, SGKL, serum/glucocorticoid regulated kinase family member 3

External IDs

MGI: 2182368 HomoloGene: 56582 GeneCards: SGK3

Gene ontology
Molecular function	• transferase activity • protein kinase activity • nucleotide binding • sodium channel regulator activity • calcium channel regulator activity • kinase activity • potassium channel regulator activity • protein binding • phosphatidylinositol binding • chloride channel regulator activity • ATP binding • protein serine/threonine kinase activity
Cellular component	• recycling endosome • cytosol • endosome • early endosome • cytoplasmic vesicle
Biological process	• regulation of apoptotic process • intracellular signal transduction • regulation of cell migration • positive regulation of transporter activity • phosphorylation • response to stress • protein phosphorylation • ion transmembrane transport • regulation of cell proliferation • peptidyl-serine phosphorylation • regulation of sequence-specific DNA binding transcription factor activity • regulation of cell growth
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


23678


170755

Ensembl


ENSG00000104205


ENSMUSG00000025915

UniProt


Q96BR1


Q9ERE3

RefSeq (mRNA)


NM_170709 NM_001033578 NM_013257


NM_001037759 NM_133220 NM_177547

RefSeq (protein)


NP_001028750 NP_037389 NP_733827 NP_001191102

NP_001032848.1 NP_573483.1 NP_808215.2 NP_001032848 NP_573483
NP_808215

Location (UCSC)

Chr 8: 66.71 – 66.86 Mb

PubMed search

NM_170709
NM_001033578
NM_013257

NM_001037759
NM_133220
NM_177547

NP_001028750
NP_037389
NP_733827
NP_001191102

NP_808215

Serine/threonine-protein kinase Sgk3 is an enzyme that in humans is encoded by the SGK3 gene.

This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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Wikipedia