SGK1

SGK1

Protein SGK1 PDB 2R5T.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2R5T, 3HDM, 3HDN

Identifiers

SGK1, SGK, serum/glucocorticoid regulated kinase 1

External IDs

MGI: 1340062 HomoloGene: 48364 GeneCards: SGK1

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • sodium channel regulator activity • calcium channel regulator activity • kinase activity • potassium channel regulator activity • protein binding • protein serine/threonine/tyrosine kinase activity • chloride channel regulator activity • ATP binding • protein serine/threonine kinase activity
Cellular component	• endoplasmic reticulum membrane • membrane • plasma membrane • endoplasmic reticulum • mitochondrion • nucleus • cytoplasm • cytosol • nuclear speck
Biological process	• regulation of apoptotic process • intracellular signal transduction • regulation of cell migration • positive regulation of transporter activity • phosphorylation • sodium ion transport • response to stress • cellular response to DNA damage stimulus • regulation of blood pressure • protein phosphorylation • ion transmembrane transport • regulation of cell proliferation • regulation of sequence-specific DNA binding transcription factor activity • regulation of cell growth • regulation of catalytic activity • renal sodium ion absorption • regulation of gastric acid secretion • apoptotic process • peptidyl-serine phosphorylation • long-term memory • neuron projection morphogenesis
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE SGK 201739 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


6446


20393


ENSG00000118515


ENSMUSG00000019970


O00141


Q9WVC6

RefSeq (mRNA)


NM_001143676 NM_001143677 NM_001143678 NM_001291995 NM_005627

NM_001161845 NM_001161847 NM_001161848 NM_001161849 NM_001161850
NM_011361

RefSeq (protein)


NP_001137148 NP_001137149 NP_001137150 NP_001278924 NP_005618

NP_001155317 NP_001155319 NP_001155320 NP_001155321 NP_001155322
NP_035491

Location (UCSC)

Chr 6: 134.17 – 134.32 Mb

Chr 10: 21.88 – 22 Mb

PubMed search

2R5T, 3HDM, 3HDN

ENSG00000118515

ENSMUSG00000019970

NM_001143676
NM_001143677
NM_001143678
NM_001291995
NM_005627

NP_001137148
NP_001137149
NP_001137150
NP_001278924
NP_005618

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Wikipedia

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