SFRS12

SREK1
Identifiers
Aliases	SREK1, SFRS12, SRrp508, SRrp86, splicing regulatory glutamic acid/lysine-rich protein 1, splicing regulatory glutamic acid and lysine rich protein 1
External IDs	MGI: 2145245 HomoloGene: 10581 GeneCards: SREK1
Gene ontology Molecular function • protein binding • nucleic acid binding • RNA binding Cellular component • spliceosomal complex • nucleus • nucleoplasm • nuclear speck Biological process • mRNA processing • RNA splicing • regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	140890	218543
Ensembl	ENSG00000153914	ENSMUSG00000032621
UniProt	Q8WXA9	Q8BZX4
RefSeq (mRNA)	NM_001077199 NM_001270492 NM_001270493 NM_139168 NM_001323527 NM_001323529 NM_001323533 NM_001323534 NM_001323535	NM_172592
RefSeq (protein)	NP_001070667 NP_001257421 NP_001310456 NP_001310458 NP_001310462 NP_001310463 NP_001310464 NP_631907	NP_766180.1 NP_766180
Location (UCSC)	Chr 5: 66.14 – 66.18 Mb	Chr 13: 103.74 – 103.77 Mb
PubMed search

140890

218543

ENSG00000153914

ENSMUSG00000032621

Q8WXA9

Q8BZX4

NM_001323529
NM_001323533
NM_001323534
NM_001323535

NM_172592

NP_001310463
NP_001310464
NP_631907

NP_766180.1
NP_766180

Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the SFRS12 gene.

SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002).[supplied by OMIM]

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Wikipedia