SEMA4D

SEMA4D
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1OLZ, 3OL2
Identifiers
Aliases	SEMA4D, C9orf164, CD100, M-sema-G, SEMAJ, coll-4, semaphorin 4D
External IDs	MGI: 109244 HomoloGene: 21282 GeneCards: SEMA4D
Gene ontology Molecular function • receptor binding • transmembrane signaling receptor activity • receptor activity • protein binding • semaphorin receptor binding • neuropilin binding Cellular component • integral component of membrane • integral component of plasma membrane • membrane • plasma membrane • extracellular space Biological process • regulation of dendrite morphogenesis • negative regulation of apoptotic process • positive regulation of phosphatidylinositol 3-kinase signaling • multicellular organism development • leukocyte aggregation • nervous system development • negative regulation of cell adhesion • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of axonogenesis • semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis • regulation of cell projection organization • negative regulation of osteoblast differentiation • positive regulation of collateral sprouting • regulation of cell shape • negative regulation of peptidyl-tyrosine phosphorylation • cell differentiation • positive regulation of protein phosphorylation • semaphorin-plexin signaling pathway • cell adhesion • immune response • ossification involved in bone maturation • positive regulation of cell migration • negative regulation of transcription from RNA polymerase II promoter • positive regulation of GTPase activity • negative regulation of alkaline phosphatase activity • negative chemotaxis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10507	20354
Ensembl	ENSG00000187764	ENSMUSG00000021451
UniProt	Q92854	O09126
RefSeq (mRNA)	NM_001142287 NM_006378 NM_182635	NM_001281880 NM_013660
RefSeq (protein)	NP_001135759 NP_006369	NP_001268809.1 NP_038688.2 NP_001268809 NP_038688
Location (UCSC)	Chr 9: 89.36 – 89.5 Mb	Chr 13: 51.7 – 51.79 Mb
PubMed search

1OLZ, 3OL2

10507

20354

ENSG00000187764

ENSMUSG00000021451

Q92854

O09126

NM_001142287
NM_006378
NM_182635

NM_001281880
NM_013660

NP_001135759
NP_006369

NP_001268809.1
NP_038688.2
NP_001268809
NP_038688

Semaphorin-4D (SEMA4D) also known as Cluster of Differentiation 100 (CD100), is a protein of the semaphorin family that in humans is encoded by the SEMA4D gene.

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Wikipedia