SEC23A

SEC23A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2NUP, 2NUT, 2YRC, 2YRD, 3EFO, 3EG9, 3EGD, 3EGX
Identifiers
Aliases	SEC23A, CLSD, Sec23 homolog A, coat complex II component
External IDs	MGI: 1349635 HomoloGene: 4642 GeneCards: SEC23A
Gene ontology Molecular function • zinc ion binding • protein binding Cellular component • cytosol • Golgi apparatus • endoplasmic reticulum membrane • membrane • Golgi membrane • smooth endoplasmic reticulum membrane • endoplasmic reticulum • perinuclear region of cytoplasm • COPII vesicle coat • ER to Golgi transport vesicle membrane • ER to Golgi transport vesicle Biological process • antigen processing and presentation of exogenous peptide antigen via MHC class II • antigen processing and presentation of peptide antigen via MHC class I • ER to Golgi vesicle-mediated transport • COPII vesicle coating • transport • protein transport • intracellular protein transport • vesicle-mediated transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10484	20334
Ensembl	ENSG00000100934	ENSMUSG00000020986
UniProt	Q15436	Q01405
RefSeq (mRNA)	NM_006364	NM_009147
RefSeq (protein)	NP_006355	NP_033173.2 NP_033173
Location (UCSC)	Chr 14: 39.03 – 39.11 Mb	Chr 12: 58.96 – 59.01 Mb
PubMed search

2NUP, 2NUT, 2YRC, 2YRD, 3EFO, 3EG9, 3EGD, 3EGX

10484

20334

ENSG00000100934

ENSMUSG00000020986

Q15436

Q01405

NM_006364

NM_009147

NP_006355

NP_033173.2
NP_033173

Sec23 homolog A (S. cerevisiae), also known as SEC23A, is a protein which in humans is encoded by the SEC23A gene.

The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It contains a gelsolin domain. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking.

...
Wikipedia