SDHD

SDHD
Identifiers
Aliases	SDHD, CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS, succinate dehydrogenase complex subunit D
External IDs	OMIM: 602690 MGI: 1914175 HomoloGene: 37718 GeneCards: SDHD
Gene ontology Molecular function • electron carrier activity • succinate dehydrogenase activity • metal ion binding • succinate dehydrogenase (ubiquinone) activity • heme binding • ubiquinone binding Cellular component • integral component of membrane • mitochondrial inner membrane • mitochondrial envelope • mitochondrion • membrane • mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) Biological process • tricarboxylic acid cycle • oxidation-reduction process • mitochondrial electron transport, succinate to ubiquinone Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6392	66925
Ensembl	ENSG00000204370	ENSMUSG00000000171
UniProt	O14521	Q9CXV1
RefSeq (mRNA)	NM_001276503 NM_001276504 NM_001276506 NM_003002	NM_025848
RefSeq (protein)	NP_001263432 NP_001263433 NP_001263435 NP_002993	NP_080124.1 NP_080124
Location (UCSC)	Chr 11: 112.09 – 112.12 Mb	Chr 9: 50.6 – 50.6 Mb
PubMed search

6392

66925

ENSG00000204370

ENSMUSG00000000171

O14521

Q9CXV1

NM_001276503
NM_001276504
NM_001276506
NM_003002

NM_025848

NP_001263432
NP_001263433
NP_001263435
NP_002993

NP_080124.1
NP_080124

Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS), also known as succinate dehydrogenase complex subunit D (SDHD), is a protein that in humans is encoded by the SDHD gene. Names previously used for SDHD were PGL and PGL1. Succinate dehydrogenase is an important enzyme in both the citric acid cycle and the electron transport chain.

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