SCN4B

SCN4B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4MZ2, 4MZ3
Identifiers
Aliases	SCN4B, ATFB17, LQT10, Navbeta4, sodium voltage-gated channel beta subunit 4
External IDs	OMIM: 608256 MGI: 2687406 HomoloGene: 18384 GeneCards: SCN4B
Gene ontology Molecular function • sodium channel regulator activity • ion channel binding • sodium channel activity • voltage-gated ion channel activity • voltage-gated sodium channel activity involved in cardiac muscle cell action potential • voltage-gated sodium channel activity Cellular component • voltage-gated sodium channel complex • integral component of membrane • membrane • intercalated disc • intrinsic component of plasma membrane • plasma membrane Biological process • cardiac muscle contraction • sodium ion transmembrane transport • sodium ion transport • regulation of ion transmembrane transport • cardiac muscle cell action potential involved in contraction • ion transport • regulation of sodium ion transmembrane transporter activity • positive regulation of sodium ion transport • AV node cell action potential • regulation of heart rate by cardiac conduction • membrane depolarization during cardiac muscle cell action potential • regulation of ventricular cardiac muscle cell membrane repolarization • regulation of postsynaptic membrane potential • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6330	399548
Ensembl	ENSG00000177098	ENSMUSG00000046480
UniProt	Q8IWT1	Q7M729
RefSeq (mRNA)	NM_001142348 NM_001142349 NM_174934	NM_001013390
RefSeq (protein)	NP_001135820 NP_001135821 NP_777594	NP_001013408
Location (UCSC)	Chr 11: 118.13 – 118.15 Mb	Chr 9: 45.14 – 45.15 Mb
PubMed search

4MZ2, 4MZ3

6330

399548

ENSG00000177098

ENSMUSG00000046480

Q8IWT1

Q7M729

NM_001142348
NM_001142349
NM_174934

NM_001013390

NP_001135820
NP_001135821
NP_777594

NP_001013408

Sodium channel β-subunit 4, also known as SCN4B or Naβ4, is an auxiliary sodium channel subunit that can alter the kinetics of sodium channels. The protein is encoded by the SCN4B gene. Mutations in the SCN4B are associated with long QT syndrome.

SCN4B might additionally function as a cell adhesion molecule.

...
Wikipedia