SCN1A

SCN1A
Identifiers
Aliases	SCN1A, EIEE6, FEB3, FEB3A, FHM3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI, sodium voltage-gated channel alpha subunit 1
External IDs	MGI: 98246 HomoloGene: 21375 GeneCards: SCN1A
Gene ontology Molecular function • sodium channel activity • voltage-gated ion channel activity • ion channel activity • voltage-gated sodium channel activity Cellular component • voltage-gated sodium channel complex • integral component of membrane • membrane • nucleoplasm • plasma membrane • nuclear body • intercalated disc • Z disc • T-tubule • axon • node of Ranvier • sodium channel complex • neuronal cell body • axon initial segment Biological process • membrane depolarization during action potential • sodium ion transmembrane transport • regulation of ion transmembrane transport • ion transport • transmembrane transport • ion transmembrane transport • sodium ion transport • regulation of postsynaptic membrane potential • cardiac muscle cell action potential involved in contraction • action potential • adult walking behavior • neuronal action potential propagation • neuronal action potential • regulation of membrane potential • neuromuscular process controlling posture • detection of mechanical stimulus involved in sensory perception of pain • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6323	20265
Ensembl	ENSG00000144285	ENSMUSG00000064329
UniProt	P35498	A2APX8
RefSeq (mRNA)	NM_001165963 NM_001165964 NM_001202435 NM_006920	NM_018733 NM_001313997
RefSeq (protein)	NP_001159435 NP_001159436 NP_001189364 NP_008851	NP_001300926 NP_061203
Location (UCSC)	Chr 2: 165.99 – 166.15 Mb	Chr 2: 66.27 – 66.44 Mb
PubMed search

6323

20265

ENSG00000144285

ENSMUSG00000064329

P35498

A2APX8

NM_001165963
NM_001165964
NM_001202435
NM_006920

NM_018733
NM_001313997

NP_001159435
NP_001159436
NP_001189364
NP_008851

NP_001300926
NP_061203

Na_v1.1, also known as the sodium channel, voltage-gated, type I, alpha subunit (SCN1A), is a protein which in humans is encoded by the SCN1A gene.

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Wikipedia