SCG5

SCG5
Identifiers
Aliases	SCG5, 7B2, P7B2, SGNE1, SgV, secretogranin V
External IDs	MGI: 98289 HomoloGene: 37722 GeneCards: SCG5
Gene ontology Molecular function • unfolded protein binding • enzyme inhibitor activity • GTP binding • protein binding Cellular component • extracellular region • secretory granule Biological process • regulation of hormone secretion • intracellular protein transport • neuropeptide signaling pathway • peptide hormone processing • negative regulation of catalytic activity • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6447	20394
Ensembl	n/a	ENSMUSG00000023236
UniProt	P05408	P12961
RefSeq (mRNA)	NM_001144757 NM_003020	NM_009162
RefSeq (protein)	NP_001138229 NP_003011	NP_033188.3 NP_033188
Location (UCSC)	Chr 15: 32.64 – 32.7 Mb	Chr 2: 113.78 – 113.83 Mb
PubMed search

6447

20394

n/a

ENSMUSG00000023236

P05408

P12961

NM_001144757
NM_003020

NM_009162

NP_001138229
NP_003011

NP_033188.3
NP_033188

Neuroendocrine protein 7B2 is a protein that in humans is encoded by the SCG5 gene. The protein expressed by this gene is widely distributed in neuroendocrine tissues. It functions as a chaperone protein for the proprotein convertase PC2 by blocking the aggregation of this protein and is required for the production of an active PC2 enzyme. It is an intrinsically disordered protein that may also function as a chaperone for other proteins in addition to proPC2.

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Wikipedia