SB-242084

SB-242084
Identifiers

IUPAC name 6-chloro-5-methyl-N-{6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl}indoline-1-carboxamide
CAS Number	181632-25-7
PubChem CID	3644637
IUPHAR/BPS	193
ChemSpider	2878619
ChEMBL	CHEMBL14563
Chemical and physical data
Formula	C₂₁H₁₉ClN₄O₂
Molar mass	394.853 g/mol
3D model (Jmol)	Interactive image
SMILES Cc1cc2CCN(c2cc1Cl)C(=O)Nc(cc4)cnc4Oc3cccnc3C
InChI InChI=1S/C21H19ClN4O2/c1-13-10-15-7-9-26(18(15)11-17(13)22)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27) Key:GIUZEIJUFOPTMR-UHFFFAOYSA-N

SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT_2C receptor. It has anxiolytic effects, and enhances dopamine signalling in the limbic system, as well as having complex effects on the dopamine release produced by cocaine, increasing it in some brain regions but reducing it in others. It has been shown to increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. In animal studies, SB-242084 produced stimulant-type activity and reinforcing effects, somewhat similar to but much weaker than cocaine or amphetamines.

...
Wikipedia