S1PR2

S1PR2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ZTI
Identifiers
Aliases	S1PR2, AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2, DFNB68, sphingosine-1-phosphate receptor 2
External IDs	MGI: 99569 HomoloGene: 3118 GeneCards: S1PR2
Gene ontology Molecular function • signal transducer activity • lipid binding • G-protein coupled receptor binding • G-protein coupled receptor activity • integrin binding • protein binding • sphingosine-1-phosphate receptor activity Cellular component • membrane • integral component of membrane • plasma membrane Biological process • activation of MAPK activity • actin cytoskeleton reorganization • positive regulation of establishment of endothelial barrier • positive regulation of cell proliferation • negative regulation of excitatory postsynaptic potential • G-protein coupled receptor signaling pathway • filopodium assembly • signal transduction • positive regulation of peptidyl-threonine phosphorylation • sphingosine-1-phosphate signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9294	14739
Ensembl	ENSG00000267534	ENSMUSG00000043895
UniProt	O95136	P52592
RefSeq (mRNA)	NM_004230	NM_010333
RefSeq (protein)	NP_004221	NP_034463
Location (UCSC)	Chr 19: 10.22 – 10.23 Mb	Chr 9: 20.96 – 20.98 Mb
PubMed search

1ZTI

9294

14739

ENSG00000267534

ENSMUSG00000043895

O95136

P52592

NM_004230

NM_010333

NP_004221

NP_034463

Sphingosine-1-phosphate receptor 2 also known as S1PR2 or S1P₂ is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).

This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

...
Wikipedia