S100A8

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1MR8, 1XK4, 4GGF, 4XJK, 5HLO, 5HLV

Identifiers

Aliases

S100A8, 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8, S100 calcium binding protein A8

External IDs

MGI: 88244 HomoloGene: 2225 GeneCards: S100A8

Gene location (Human)

Chr.	Chromosome 1 (human)

Band	No data available	Start	153,390,032 bp
Band	No data available	End	153,391,188 bp

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)

Band	No data available	Start	90,668,978 bp
Band	No data available	End	90,670,035 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• Toll-like receptor 4 binding • RAGE receptor binding • microtubule binding • protein binding • calcium ion binding • arachidonic acid binding • zinc ion binding • metal ion binding
Cellular component	• nucleus • cytoskeleton • cytosol • extracellular exosome • membrane • plasma membrane • cytoplasm • extracellular region • extracellular space • secretory granule lumen • intermediate filament cytoskeleton
Biological process	• regulation of inflammatory response • activation of cysteine-type endopeptidase activity involved in apoptotic process • immune system process • positive regulation of inflammatory response • neutrophil chemotaxis • positive regulation of intrinsic apoptotic signaling pathway • defense response to fungus • response to ethanol • chemokine production • response to zinc ion • acute inflammatory response • defense response to bacterium • leukocyte migration involved in inflammatory response • peptidyl-cysteine S-nitrosylation • sequestering of zinc ion • neutrophil aggregation • response to lipopolysaccharide • chemotaxis • positive regulation of peptide secretion • chronic inflammatory response • astrocyte development • wound healing • apoptotic process • positive regulation of cell growth • autophagy • inflammatory response • regulation of cytoskeleton organization • cytokine production • positive regulation of NF-kappaB transcription factor activity • innate immune response • toll-like receptor signaling pathway • antimicrobial humoral response • neutrophil degranulation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


6279


20201

Ensembl


ENSG00000143546


ENSMUSG00000056054

UniProt


P05109


P27005

RefSeq (mRNA)


NM_002964 NM_001319196 NM_001319197 NM_001319198 NM_001319201


NM_013650

RefSeq (protein)


NP_001306125 NP_001306126 NP_001306127 NP_001306130 NP_002955


NP_038678

Location (UCSC)

Chr 1: 153.39 – 153.39 Mb

Chr 1: 90.67 – 90.67 Mb

PubMed search

1MR8, 1XK4, 4GGF, 4XJK, 5HLO, 5HLV

NM_002964
NM_001319196
NM_001319197
NM_001319198
NM_001319201

NM_013650

NP_001306125
NP_001306126
NP_001306127
NP_001306130
NP_002955

...
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