S100A10

S100A10
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1A4P, 1BT6, 4DRW, 4FTG, 4HRE, 4HRG, 4HRH
Identifiers
Aliases	S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10, S100 calcium binding protein A10
External IDs	MGI: 1339468 HomoloGene: 2228 GeneCards: S100A10
Gene location (Human) Chr. Chromosome 1 (human) Band 1q21.3 Start 151,982,915 bp End 151,994,390 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3 F2.1|3 40.51 cM Start 93,555,080 bp End 93,564,643 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • calcium ion binding • protein binding • protein homodimerization activity • ion channel binding • lipid binding Cellular component • membrane raft • extrinsic component of plasma membrane • extracellular exosome • endoplasmic reticulum • extracellular region Biological process • positive regulation of focal adhesion assembly • positive regulation of GTPase activity • positive regulation of substrate adhesion-dependent cell spreading • positive regulation of binding • protein heterotetramerization • membrane raft assembly • vesicle budding from membrane • positive regulation of stress fiber assembly • response to drug • protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6281	20194
Ensembl	ENSG00000197747	ENSMUSG00000041959
UniProt	P60903	P08207
RefSeq (mRNA)	NM_002966	NM_009112
RefSeq (protein)	NP_002957	NP_033138
Location (UCSC)	Chr 1: 151.98 – 151.99 Mb	Chr 1: 93.56 – 93.56 Mb
PubMed search

1A4P, 1BT6, 4DRW, 4FTG, 4HRE, 4HRG, 4HRH

6281

20194

ENSG00000197747

ENSMUSG00000041959

P60903

P08207

NM_002966

NM_009112

NP_002957

NP_033138

S100 calcium-binding protein A10 (S100A10), also known as p11, is a protein that is encoded by the S100A10 gene in humans and the S100a10 gene in other species. S100A10 is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells. They regulate a number of cellular processes such as cell cycle progression and differentiation. The S100 protein is implicated in exocytosis and endocytosis by reorganization of F-actin.

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