"My Boo" is the only single released by the Atlanta-based hip hop group Ghost Town DJ's. It was released on Jermaine Dupri's So So Def label and Columbia Records, on the compilation album So So Def Bass All-Stars. The song, an invite by a female to a male, blends R&B-style vocals over a hip hop beat. It was written by Carlton Mahone, Rodney Terry and Lil Jon, with lead vocals sung by Virgo Williams. The song peaked at #31 on the Billboard Hot 100 on its initial release in 1996. In 2016, the song was re-popularized by the "Running Man Challenge" and re-entered the Hot 100 giving it a new peak of #27 twenty years after its original release.

Virgo Williams was working on becoming a solo artist, and she was originally intended to provide background vocals for My Boo for another artist named Akema, but she was not able to work with the song, and it was decided that Williams' version of the song was better and Williams' vocals became the lead vocals. Lil Jon was an A&R Director for So So Def at the time, and oversaw the production of the song. He was also the executive producer of the song, but could not take credit for the production because of his job position. Terry also produced it, and it was the second version of the beat currently used in the song.

The music video features a pool party. The group does not appear in the video.

"My Boo" entered the Billboard charts on the issue dated June 15, 1996 with its number 71 debut on the Hot R&B Airplay chart, with early airplay concentrated at Southern R&B radio stations. Three weeks later, following its commercial release as a vinyl 12-inch single, it entered the Hot R&B Singles and Hot 100 charts at numbers 41 and 65, respectively. On the latter chart, where it was the highest-ranking debut of the week, nearly 85% of the single's chart points were derived from airplay, with its vinyl-only release precluding a larger contribution from sales. Though it was ultimately never released domestically in the more popular cassette and CD configurations, the single managed to peak at numbers 18 and 31 on Hot R&B Singles and the Hot 100, respectively. The song was especially popular at rhythmic radio stations, peaking at number 2 on the Top 40/Rhythm-Crossover chart.

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