Rosemeadow owes its name to early settler Thomas Rose, who in 1818 bought a farm called Mount Gilead which covered parts of modern-day Rosemeadow and neighbouring Gilead. Rose was a baker and publican as well as a farmer, building a mill on his property and a couple of large dams which helped him and his neighbours survive the drought of 1829.

The area remained farmland until the mid-1970s when Sydney's urban sprawl reached it and the suburb was officially named in 1976. The Rosemeadow public housing estate is an example of the American Radburn design for public housing which turns houses around so they back on to streets with the fronts facing each other. This design has been criticised in Sydney as contributing to social problems and following an incident of street violence in 2009 orders were made to partially demolish the estate. Since the partial demolishing of the suburb, the streets have begun to be renamed.

Rosemeadow Marketplace, on the corner of Copperfield Drive and Fitzgibbon Lane, is a medium-sized shopping centre. The local post office sits within the Marketplace and nearby is a community health centre, fire station, high school and an Anglican church.

John Therry Catholic High School is the oldest school in the suburb, having opened in 1981. Next door is its feeder school, Our Lady Help of Christians Parish School. Public schools include Rosemeadow Public, Ambarvale High and Mary Brooksbank Special School.

There are a number of parks and reserves within or boarding Rosemeadow. These are:

Rosemeadow can be accessed via Appin Road or via surrounding suburbs of Ambarvale and Glen Alpine. The suburb is serviced by Busabout buses, which provide links to Macarthur and Campbelltown railway stations as well as occasional services to Appin and Wollongong.

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Wikipedia