Rhodopsin

RHO
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ZWJ, 5DGY
Identifiers
Aliases	RHO, CSNBAD1, OPN2, RP4, rhodopsin, Rhodopsin, visual purple
External IDs	OMIM: 180380 MGI: 97914 HomoloGene: 68068 GeneCards: RHO
Gene ontology Molecular function • signal transducer activity • metal ion binding • photoreceptor activity • protein binding • G-protein coupled receptor activity Cellular component • Golgi-associated vesicle membrane • integral component of membrane • photoreceptor disc membrane • Golgi apparatus • Golgi membrane • photoreceptor outer segment • cell-cell junction • integral component of plasma membrane • membrane • photoreceptor inner segment • ciliary membrane • plasma membrane • photoreceptor inner segment membrane • photoreceptor outer segment membrane Biological process • retina development in camera-type eye • sensory perception of light stimulus • signal transduction • response to stimulus • detection of light stimulus • absorption of visible light • cellular response to light stimulus • protein phosphorylation • response to light stimulus • regulation of rhodopsin mediated signaling pathway • retinoid metabolic process • phototransduction • phototransduction, visible light • photoreceptor cell maintenance • visual perception • protein-chromophore linkage • G-protein coupled receptor signaling pathway • rhodopsin mediated signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6010	212541
Ensembl	ENSG00000163914	ENSMUSG00000030324
UniProt	P08100	P15409
RefSeq (mRNA)	NM_000539	NM_145383
RefSeq (protein)	NP_000530	NP_663358.1 NP_663358
Location (UCSC)	Chr 3: 129.53 – 129.54 Mb	Chr 6: 115.93 – 115.94 Mb
PubMed search

4ZWJ, 5DGY

6010

212541

ENSG00000163914

ENSMUSG00000030324

P08100

P15409

NM_000539

NM_145383

NP_000530

NP_663358.1
NP_663358

Rhodopsin (also known as visual purple) is a light-sensitive receptor protein involved in visual phototransduction. It is named after ancient Greek ῥόδον (rhódon) for “rose”, due to its pinkish color, and ὄψις (ópsis) for “sight”. Rhodopsin is a biological pigment found in the rods of the retina and is a G-protein-coupled receptor (GPCR). Rhodopsin is extremely sensitive to light, and thus enables vision in low-light conditions. When rhodopsin is exposed to light, it immediately photobleaches. In humans, it is regenerated fully in about 30 minutes; after which rods are more sensitive.

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