Rev-ErbA

nuclear receptor subfamily 1, group D, member 1
Identifiers
Symbol	NR1D1
Alt. symbols	ear-1, hRev, Rev-ErbAalpha, THRA1
Entrez	9572
HUGO	7962
OMIM	602408
RefSeq	NM_021724
UniProt	P20393
Other data
Locus	Chr. 17 q11.2

nuclear receptor subfamily 1, group D, member 2
Identifiers
Symbol	NR1D2
Alt. symbols	BD73, RVR, EAR-1r, HZF2, Hs.37288
Entrez	9975
HUGO	7963
OMIM	602304
RefSeq	XM_001130839
UniProt	Q14995
Other data
Locus	Chr. 3 p24.1

The Rev-ErbA proteins are members of the nuclear receptor family of intracellular transcription factors. There are two forms of the receptor, alpha and beta, each encoded by a separate gene (NR1D1 and NR1D2 respectively).

The rev-Erb-α gene is highly unusual in that it is encoded on the opposite strand of the alpha-thyroid hormone receptor (TR) gene.

The rev-Erb-α protein is a key regulatory component of the circadian clock. In addition, rev-Erb-α appears also to regulate the breakdown of cartilage.

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Wikipedia