Reuben Chase (June 23, 1754 – June 23, 1824) was an officer in the Continental Navy.
Chase joined Ranger as a seaman in 1777 and served during John Paul Jones' daring raid into British waters. Chase was appointed a midshipman in Bonhomme Richard March 18, 1779, and took part in the historic victory over HMS Serapis September 23, 1779.
Chase (DD-323) was named in his honor.