Reston virus (RESTV) | |
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An electron micrograph of Reston virus | |
Virus classification | |
Group: | Group V ((−)ssRNA) |
Order: | Mononegavirales |
Family: | Filoviridae |
Genus: | Ebolavirus |
Species: | Reston ebolavirus |
Member virus (Abbreviation) | |
Reston virus (RESTV) |
Reston virus (RESTV)
Reston virus (RESTV) is one of five known viruses within the genus Ebolavirus. Reston virus causes Ebola virus disease in non-human primates; unlike the other four ebolaviruses, it is not known to cause disease in humans, but has caused asymptomatic infections. Reston virus was first described in 1990 as a new "strain" of Ebola virus (EBOV). It is the single member of the species Reston ebolavirus, which is included into the genus Ebolavirus, family Filoviridae, order Mononegavirales. Reston virus is named after Reston, Virginia, US, where the virus was first discovered.
RESTV was discovered in crab-eating macaques from Hazleton Laboratories (now Covance) in 1989. This attracted significant media attention due to the proximity of Reston to the Washington, DC, metro area and the lethality of a closely related Ebola virus. Despite its status as a level-4 organism, Reston virus is non-pathogenic to humans, though hazardous to monkeys; the perception of its lethality was compounded by the monkey's coinfection with Simian hemorrhagic fever virus (SHFV).
Reston virus is pronounced ‘rɛstən vɑɪrəs (IPA) or res-tuhn vahy-ruhs in English phonetic notation. According to the rules for taxon naming established by the International Committee on Taxonomy of Viruses (ICTV), the name Reston virus is always to be capitalized, but is never italicized, and may be abbreviated (with RESTV being the official abbreviation).