Replication protein A2

RPA2

Protein RPA2 PDB 1dpu.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1DPU, 1L1O, 1QUQ, 1Z1D, 2PI2, 2PQA, 2Z6K, 3KDF, 4MQV, 4OU0

Identifiers

RPA2, REPA2, RP-A p32, RP-A p34, RPA32, replication protein A2

External IDs

MGI: 1339939 HomoloGene: 37712 GeneCards: RPA2

Gene location (Human)

Chr.	Chromosome 1 (human)

Band	1p35.3	Start	27,891,524 bp
Band	1p35.3	End	27,914,746 bp

Gene location (Mouse)

Chr.	Chromosome 4 (mouse)

Band	4\|4 D2.3	Start	132,768,332 bp
Band	4\|4 D2.3	End	132,778,752 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• DNA binding • protein N-terminus binding • single-stranded DNA binding • damaged DNA binding • protein binding • enzyme binding • protein phosphatase binding • ubiquitin protein ligase binding • G-rich strand telomeric DNA binding
Cellular component	• site of double-strand break • PML body • nucleoplasm • chromosome, telomeric region • DNA replication factor A complex • chromatin • nucleus • nuclear chromosome, telomeric region • nuclear body
Biological process	• nucleotide-excision repair, DNA gap filling • DNA recombination • interstrand cross-link repair • regulation of double-strand break repair via homologous recombination • error-free translesion synthesis • G1/S transition of mitotic cell cycle • error-prone translesion synthesis • cellular response to DNA damage stimulus • DNA replication • mitotic G1 DNA damage checkpoint • regulation of DNA damage checkpoint • regulation of cellular response to heat • mismatch repair • translesion synthesis • transcription-coupled nucleotide-excision repair • nucleotide-excision repair, DNA incision • DNA damage response, detection of DNA damage • base-excision repair • nucleotide-excision repair • nucleotide-excision repair, preincision complex stabilization • regulation of signal transduction by p53 class mediator • DNA repair • double-strand break repair via homologous recombination • nucleotide-excision repair, preincision complex assembly • nucleotide-excision repair, DNA incision, 5'-to lesion • nucleotide-excision repair, DNA incision, 3'-to lesion • protein localization to chromosome • telomere maintenance • telomere maintenance via semi-conservative replication
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


6118


19891


ENSG00000117748


ENSMUSG00000028884


P15927


Q62193

RefSeq (mRNA)


NM_001286076 NM_001297558 NM_002946


NM_011284

RefSeq (protein)


NP_001273005 NP_001284487 NP_002937


n/a

Location (UCSC)

Chr 1: 27.89 – 27.91 Mb

Chr 1: 132.77 – 132.78 Mb

PubMed search

1DPU, 1L1O, 1QUQ, 1Z1D, 2PI2, 2PQA, 2Z6K, 3KDF, 4MQV, 4OU0

ENSG00000117748

ENSMUSG00000028884

NM_001286076
NM_001297558
NM_002946

NP_001273005
NP_001284487
NP_002937

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Wikipedia

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