Replication protein A1

RPA1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1EWI, 1FGU, 1JMC, 1L1O, 2B29, 2B3G, 4IJH, 4IJL, 4IPC, 4IPD, 4IPG, 4IPH, 4LUO, 4LUV, 4LUZ, 4LW1, 4LWC, 4NB3, 4O0A, 4R4C, 4R4I, 4R4O, 4R4Q, 4R4T, 5E7N, 5EAY
Identifiers
Aliases	RPA1, HSSB, MST075, REPA1, RF-A, RP-A, RPA70, Replication protein A1
External IDs	MGI: 1915525 HomoloGene: 2208 GeneCards: RPA1
Gene location (Human) Chr. Chromosome 17 (human) Band 17p13.3 Start 1,829,702 bp End 1,900,082 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11 B5|11 45.79 cM Start 75,298,166 bp End 75,348,324 bp
Gene ontology Molecular function • DNA binding • metal ion binding • single-stranded DNA binding • damaged DNA binding • protein binding • nucleic acid binding • G-rich strand telomeric DNA binding Cellular component • PML body • nucleoplasm • DNA replication factor A complex • nuclear chromosome, telomeric region • cell nucleus Biological process • DNA-dependent DNA replication • nucleotide-excision repair, DNA gap filling • DNA recombination • interstrand cross-link repair • error-free translesion synthesis • G1 phase • error-prone translesion synthesis • cellular response to DNA damage stimulus • DNA replication • regulation of cellular response to heat • mismatch repair • translesion synthesis • transcription-coupled nucleotide-excision repair • nucleotide-excision repair, DNA incision • DNA damage response, detection of DNA damage • nucleotide-excision repair, DNA incision, 3'-to lesion • nucleotide-excision repair, DNA incision, 5'-to lesion • nucleotide-excision repair, preincision complex stabilization • nucleotide-excision repair • DNA repair • base-excision repair • regulation of signal transduction by p53 class mediator • double-strand break repair via homologous recombination • nucleotide-excision repair, preincision complex assembly • protein localization to chromosome • telomere maintenance • telomere maintenance via semi-conservative replication Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6117	68275
Ensembl	ENSG00000132383	ENSMUSG00000000751
UniProt	P27694	Q8VEE4
RefSeq (mRNA)	NM_002945 NM_001355120 NM_001355121	NM_001164223 NM_026653
RefSeq (protein)	NP_002936 NP_001342049 NP_001342050	NP_001157695 NP_080929
Location (UCSC)	Chr 17: 1.83 – 1.9 Mb	Chr 11: 75.3 – 75.35 Mb
PubMed search

1EWI, 1FGU, 1JMC, 1L1O, 2B29, 2B3G, 4IJH, 4IJL, 4IPC, 4IPD, 4IPG, 4IPH, 4LUO, 4LUV, 4LUZ, 4LW1, 4LWC, 4NB3, 4O0A, 4R4C, 4R4I, 4R4O, 4R4Q, 4R4T, 5E7N, 5EAY

6117

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