René Primevère Lesson (20 March 1794 – 28 April 1849) was a French surgeon, naturalist, ornithologist, and herpetologist.
He was born at Rochefort, and entered the Naval Medical School in Rochefort at the age of sixteen. He served in the French Navy during the Napoleonic Wars; in 1811 he was third surgeon on the frigate Saale, and in 1813 was second surgeon on the Regulus.
In 1816 Lesson changed his classification to pharmacist. He served on Duperrey's round-the-world voyage of La Coquille (1822–25), of which he collected natural history specimens with his fellow surgeon Prosper Garnot and officer Dumont d'Urville. During his visits to the Moluccas and New Guinea, Lesson became the first naturalist to see birds of paradise in the wild.
On returning to Paris, he spent seven years preparing the section on vertebrates for the official account of the expedition: "Voyage autour du monde entrepris par ordre du Gouvernement sur la corvette La Coquille" (published from 1826 to 1839). During this time period, he also produced "Manuel d'Ornithologie" (1828), "Traité d'Ornithologie" (1831), "Centurie Zoologique" (1830–32) and "Illustrations de Zoologie" (1832–35). Lesson also published several monographs on hummingbirds and one book on birds of paradise:
In the field of herpetology he described many new species of amphibians and reptiles.