Rajah Rama Varma was the ruler of the Indian kingdom of Venad, later known as Travancore, in the modern day state of Kerala, India between 1724 and 1729, having succeeded his brother Unni Kerala Varma. He is better known as the uncle of Maharajah Padmanabha Dasa Vanchi Pala Marthanda Varma Kulasekhara Perumal, the "maker of modern Travancore". He was born as the second son of Rajah Ittamar of Thattari Kovilakam into the Royal Family of Kolathunadu. His entire family, including himself, two sisters and his elder brother Unni Kerala Varma, were adopted into the Venad house as members of the Travancore Royal Family by Rajah Ravi Varma, nephew of Umayamma Rani due to their failure of heirs there. Of his sisters, one died soon after her adoption while the other was the mother of the Maharajah Marthanda Varma.
Rajah Rama Varma was a weak ruler during whose reign the Ettuveetil Pillamar, the Ettara Yogam and other nobles had more power than the King himself, as had been the case since the middle of the 17th century. However, on the advice of Marthanda Varma, the Rajah signed a treaty of subordination with the Pandyas at Trichonopoly and secured a Pandyan force in Venad. This frightened the disloyal nobles for sometime, who now, however, turned their attention towards killing Marthanda Varma, the heir apparent under the Marumakkathayam law. Previously, the Ettuveetil Pillamar had been responsible for the assassination of prince Kerala Varma.