Radixin

RDX

Protein RDX PDB 1gc6.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1GC6, 1GC7, 1J19, 2D10, 2D11, 2D2Q, 2EMS, 2EMT, 2YVC, 2ZPY

Identifiers

RDX, DFNB24, radixin

External IDs

MGI: 97887 HomoloGene: 37707 GeneCards: RDX

Gene ontology
Molecular function	• protein homodimerization activity • protein domain specific binding • ATPase binding • protein kinase A binding • cytoskeletal protein binding • protein binding • actin binding • RNA binding • cadherin binding
Cellular component	• cytoplasm • membrane • focal adhesion • filopodium • ruffle • myelin sheath • plasma membrane • apical part of cell • stereocilium • microvillus • apical plasma membrane • cortical actin cytoskeleton • cleavage furrow • extracellular exosome • cytoskeleton • cell periphery • lamellipodium • extrinsic component of membrane • midbody • T-tubule • cell tip • extracellular space • cell-cell adherens junction
Biological process	• regulation of cell size • establishment of endothelial barrier • microvillus assembly • regulation of organelle assembly • establishment of protein localization • positive regulation of cell migration • regulation of GTPase activity • positive regulation of cellular protein catabolic process • positive regulation of G1/S transition of mitotic cell cycle • negative regulation of homotypic cell-cell adhesion • regulation of actin filament bundle assembly • positive regulation of gene expression • negative regulation of GTPase activity • negative regulation of adherens junction organization • apical protein localization • actin filament capping • cellular response to thyroid hormone stimulus • regulation of cell shape • protein kinase A signaling • regulation of ruffle assembly • positive regulation of protein localization to early endosome • positive regulation of early endosome to late endosome transport • negative regulation of cell size • establishment of protein localization to plasma membrane • regulation of Rap protein signal transduction • cellular response to platelet-derived growth factor stimulus • barbed-end actin filament capping
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE RDX 204969 s at fs.png

PBB GE RDX 212398 at fs.png

PBB GE RDX 212397 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


5962


19684


ENSG00000137710


ENSMUSG00000032050


P35241


P26043

RefSeq (mRNA)

NM_002906 NM_001260492 NM_001260493 NM_001260494 NM_001260495
NM_001260496


NM_001104616 NM_001104617 NM_009041

RefSeq (protein)

NP_001247421 NP_001247422 NP_001247423 NP_001247424 NP_001247425
NP_002897


NP_001098086.1 NP_033067.2 NP_001098086 NP_001098087 NP_033067

Location (UCSC)

Chr 11: 110.17 – 110.3 Mb

Chr 9: 52.05 – 52.09 Mb

PubMed search

1GC6, 1GC7, 1J19, 2D10, 2D11, 2D2Q, 2EMS, 2EMT, 2YVC, 2ZPY

ENSG00000137710

ENSMUSG00000032050

NM_001104616
NM_001104617
NM_009041

NP_001098086.1
NP_033067.2
NP_001098086
NP_001098087
NP_033067

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Wikipedia

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