RUNX1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1CMO, 1CO1, 1E50, 1H9D, 1LJM

Identifiers

RUNX1, AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha, runt related transcription factor 1

External IDs

Genetically Related Diseases

Gene ontology
Molecular function	• DNA binding • calcium ion binding • RNA polymerase II regulatory region sequence-specific DNA binding • core promoter binding • protein homodimerization activity • transcription factor activity, sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding • transcription factor binding • regulatory region DNA binding • protein binding • protein heterodimerization activity • ATP binding
Cellular component	• intracellular membrane-bounded organelle • nucleoplasm • nucleus • cytosol
Biological process	• peripheral nervous system neuron development • myeloid cell differentiation • hemopoiesis • regulation of transcription, DNA-templated • chondrocyte differentiation • ossification • negative regulation of granulocyte differentiation • hematopoietic stem cell proliferation • transcription, DNA-templated • positive regulation of angiogenesis • positive regulation of transcription, DNA-templated • positive regulation of interleukin-2 production • positive regulation of granulocyte differentiation • positive regulation of transcription from RNA polymerase II promoter • transcription from RNA polymerase II promoter
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


861


12394


ENSG00000159216


ENSMUSG00000022952


Q01196


Q03347

RefSeq (mRNA)


NM_001001890 NM_001122607 NM_001754


NM_001111021 NM_001111022 NM_001111023 NM_009821

RefSeq (protein)


NP_001001890 NP_001116079 NP_001745


n/a

Location (UCSC)

PubMed search

n/a