ROBO2

ROBO2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1UEM, 1UJT, 2EDJ
Identifiers
Aliases	ROBO2, SAX3, roundabout guidance receptor 2
External IDs	MGI: 1890110 HomoloGene: 43188 GeneCards: ROBO2
Genetically Related Diseases
periodontitis
Gene ontology Molecular function • protein binding • identical protein binding • axon guidance receptor activity Cellular component • integral component of membrane • membrane • cell surface • axolemma • extracellular exosome Biological process • cell differentiation • ureteric bud development • kidney development • negative regulation of synapse assembly • Roundabout signaling pathway • positive regulation of axonogenesis • nervous system development • multicellular organism development • chemotaxis • central nervous system development • cellular response to hormone stimulus • olfactory bulb interneuron development • apoptotic process involved in luteolysis • negative regulation of negative chemotaxis • axon midline choice point recognition • metanephros development • homophilic cell adhesion via plasma membrane adhesion molecules • retinal ganglion cell axon guidance • brain development • spinal cord development • axon guidance Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6092	268902
Ensembl	ENSG00000185008	ENSMUSG00000052516
UniProt	Q9HCK4	Q7TPD3
RefSeq (mRNA)	NM_001128929 NM_001290039 NM_001290040 NM_001290065 NM_002942	NM_175549
RefSeq (protein)	NP_001122401 NP_001276968 NP_001276969 NP_001276994 NP_002933	n/a
Location (UCSC)	Chr 3: 75.91 – 77.65 Mb	Chr 16: 73.89 – 74.41 Mb
PubMed search

1UEM, 1UJT, 2EDJ

6092

268902

ENSG00000185008

ENSMUSG00000052516

Q9HCK4

Q7TPD3

NM_001128929
NM_001290039
NM_001290040
NM_001290065
NM_002942

NM_175549

NP_001122401
NP_001276968
NP_001276969
NP_001276994
NP_002933

n/a

Roundabout homolog 2 is a protein that in humans is encoded by the ROBO2 gene.

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Wikipedia