ROBO1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2EO9, 2V9Q, 2V9T, 4HLJ

Identifiers

ROBO1, DUTT1, SAX3, roundabout guidance receptor 1

External IDs

Gene ontology
Molecular function	• LRR domain binding • protein binding • identical protein binding • axon guidance receptor activity
Cellular component	• cytoplasm • integral component of membrane • cell projection • membrane • integral component of plasma membrane • cell surface • axon • plasma membrane
Biological process	• positive regulation of Rho protein signal transduction • negative regulation of chemokine-mediated signaling pathway • cell differentiation • negative regulation of mammary gland epithelial cell proliferation • Roundabout signaling pathway • positive regulation of axonogenesis • nervous system development • cell migration involved in sprouting angiogenesis • axon guidance • multicellular organism development • chemotaxis • heart development • cell adhesion • negative regulation of cell migration • negative regulation of negative chemotaxis • axon midline choice point recognition • activation of cysteine-type endopeptidase activity involved in apoptotic process • chemorepulsion involved in postnatal olfactory bulb interneuron migration • homophilic cell adhesion via plasma membrane adhesion molecules
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


6091


19876


ENSG00000169855


ENSMUSG00000022883


Q9Y6N7


O89026

RefSeq (mRNA)


NM_001145845 NM_002941 NM_133631


NM_019413

RefSeq (protein)


NP_001139317 NP_002932 NP_598334


NP_062286.2 NP_062286

Location (UCSC)

PubMed search

Roundabout homolog 1 is a protein that in humans is encoded by the ROBO1 gene.