RHOB

RHOB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2FV8
Identifiers
Aliases	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6, ras homolog family member B
External IDs	OMIM: 165370 MGI: 107949 HomoloGene: 68377 GeneCards: RHOB
Gene ontology Molecular function • nucleotide binding • GDP binding • GTP binding • protein binding • GTPase activity Cellular component • cytosol • endosome • late endosome • membrane • late endosome membrane • focal adhesion • plasma membrane • early endosome • cleavage furrow • endosome membrane • extracellular exosome • nucleus • intracellular Biological process • cell differentiation • regulation of cell migration • endosome to lysosome transport • endothelial tube morphogenesis • negative regulation of cell cycle • cytokinesis • positive regulation of angiogenesis • positive regulation of endothelial cell migration • multicellular organism development • platelet activation • cell adhesion • negative regulation of cell migration • angiogenesis • Rho protein signal transduction • transport • positive regulation of apoptotic process • cellular response to ionizing radiation • protein transport • intracellular protein transport • regulation of small GTPase mediated signal transduction • cellular response to hydrogen peroxide • apoptotic process • small GTPase mediated signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	388	11852
Ensembl	ENSG00000143878	ENSMUSG00000054364
UniProt	P62745	P62746
RefSeq (mRNA)	NM_004040	NM_007483
RefSeq (protein)	NP_004031	NP_031509.1 NP_031509
Location (UCSC)	Chr 2: 20.45 – 20.45 Mb	Chr 12: 8.5 – 8.5 Mb
PubMed search

2FV8

388

11852

ENSG00000143878

ENSMUSG00000054364

P62745

P62746

NM_004040

NM_007483

NP_004031

NP_031509.1
NP_031509

Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.

RHOB is a member of the Rho GTP-binding protein family.

RHOB has been shown to interact with CIT,ARHGEF3,ARHGDIG and RHPN2.

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Wikipedia