RAR-related orphan receptor gamma

RORC
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3B0W, 3KYT, 3L0J, 3L0L, 4NB6, 4NIE, 4QM0, 4S14, 4WLB, 4WPF, 4WQP, 4XT9, 4YMQ, 4ZJR, 4ZJW, 4ZOM, 5C4O, 5APK, 5APJ, 5APH, 5C4U, 5C4S, 5C4T, 4YPQ, 5AYG, 5IXK, 5IZ0, 5EJV, 5ETH
Identifiers
Aliases	RORC, NR1F3, RORG, RZR-GAMMA, RZRG, TOR, RAR-related orphan receptor gamma, IMD42, RAR related orphan receptor C
External IDs	MGI: 104856 HomoloGene: 21051 GeneCards: RORC
Genetically Related Diseases
inflammatory bowel disease
Gene ontology Molecular function • DNA binding • sequence-specific DNA binding • transcription factor activity, direct ligand regulated sequence-specific DNA binding • transcription factor activity, sequence-specific DNA binding • zinc ion binding • metal ion binding • steroid hormone receptor activity • RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding • protein binding • oxysterol binding Cellular component • nucleoplasm • nucleus • nuclear body Biological process • regulation of transcription, DNA-templated • rhythmic process • cellular response to sterol • negative regulation of thymocyte apoptotic process • circadian regulation of gene expression • regulation of fat cell differentiation • transcription, DNA-templated • regulation of steroid metabolic process • positive regulation of transcription, DNA-templated • multicellular organism development • regulation of glucose metabolic process • regulation of transcription involved in cell fate commitment • circadian rhythm • xenobiotic metabolic process • positive regulation of circadian rhythm • adipose tissue development • T-helper 17 cell differentiation • Peyer's patch development • transcription initiation from RNA polymerase II promoter • T-helper cell differentiation • lymph node development • steroid hormone mediated signaling pathway • intracellular receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6097	19885
Ensembl	ENSG00000143365	ENSMUSG00000028150
UniProt	P51449	P51450
RefSeq (mRNA)	NM_001001523 NM_005060	NM_001293734 NM_011281
RefSeq (protein)	NP_001001523 NP_005051	NP_001280663.1 NP_035411.2 NP_001280663 NP_035411
Location (UCSC)	Chr 1: 151.81 – 151.83 Mb	Chr 3: 94.37 – 94.4 Mb
PubMed search

3B0W, 3KYT, 3L0J, 3L0L, 4NB6, 4NIE, 4QM0, 4S14, 4WLB, 4WPF, 4WQP, 4XT9, 4YMQ, 4ZJR, 4ZJW, 4ZOM, 5C4O, 5APK, 5APJ, 5APH, 5C4U, 5C4S, 5C4T, 4YPQ, 5AYG, 5IXK, 5IZ0, 5EJV, 5ETH

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