RAPGEF6

RAPGEF6
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2D93, 3LNY
Identifiers
Aliases	RAPGEF6, KIA001LB, PDZ-GEF2, PDZGEF2, RA-GEF-2, RAGEF2, Rap guanine nucleotide exchange factor 6
External IDs	MGI: 2384761 HomoloGene: 22968 GeneCards: RAPGEF6
Gene ontology Molecular function • phosphatidic acid binding • GTP-dependent protein binding • protein binding • Ras GTPase binding • guanyl-nucleotide exchange factor activity Cellular component • cytoplasm • cytosol • plasma membrane • endocytic vesicle • apical plasma membrane • membrane • centrosome Biological process • regulation of GTPase activity • small GTPase mediated signal transduction • positive regulation of GTPase activity • Ras protein signal transduction • microvillus assembly • protein localization to plasma membrane • establishment of endothelial intestinal barrier • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51735	192786
Ensembl	ENSG00000158987	ENSMUSG00000037533
UniProt	Q8TEU7	n/a
RefSeq (mRNA)	NM_016340 NM_001164386 NM_001164387 NM_001164388 NM_001164389 NM_001164390	NM_001252494 NM_001252496 NM_001252497 NM_001252498 NM_175258
RefSeq (protein)	NP_001157858 NP_001157859 NP_001157860 NP_001157861 NP_001157862 NP_057424	n/a
Location (UCSC)	Chr 5: 131.42 – 131.64 Mb	Chr 11: 54.52 – 54.7 Mb
PubMed search

2D93, 3LNY

51735

192786

ENSG00000158987

ENSMUSG00000037533

Q8TEU7

n/a

NM_001164390

NM_001252494
NM_001252496
NM_001252497
NM_001252498
NM_175258

NP_057424

n/a

Rap guanine nucleotide exchange factor 6 is a protein that in humans is encoded by the RAPGEF6 gene.

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