RAPGEF4

RAPGEF4

Protein RAPGEF4 PDB 1o7f.png

Identifiers

RAPGEF4, 2, CAMP-GEFII, CGEF2, EPAC, EPAC 2, EPAC2, Nbla00496, Rap guanine nucleotide exchange factor 4

External IDs

MGI: 1917723 HomoloGene: 4451 GeneCards: RAPGEF4

Gene ontology
Molecular function	• nucleotide binding • cAMP binding • Ras GTPase binding • protein binding • Ras guanyl-nucleotide exchange factor activity • guanyl-nucleotide exchange factor activity
Cellular component	• cytoplasm • cytosol • membrane • plasma membrane
Biological process	• G-protein coupled receptor signaling pathway • intracellular signal transduction • regulation of insulin secretion • small GTPase mediated signal transduction • insulin secretion • regulation of exocytosis • positive regulation of GTPase activity • cAMP-mediated signaling • calcium ion regulated exocytosis • exocytosis
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE RAPGEF4 205651 x at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


11069


56508


ENSG00000091428


ENSMUSG00000049044


Q8WZA2


Q9EQZ6

RefSeq (mRNA)


NM_001100397 NM_001282899 NM_001282900 NM_001282901 NM_007023


NM_001204165 NM_001204166 NM_001204167 NM_019688

RefSeq (protein)


NP_001093867 NP_001269828 NP_001269829 NP_001269830 NP_008954

NP_001191094.1 NP_001191095.1 NP_062662.1 NP_001191094 NP_001191095
NP_001191096 NP_062662

Location (UCSC)

Chr 2: 172.74 – 173.05 Mb

Chr 2: 71.98 – 72.26 Mb

PubMed search

ENSG00000091428

ENSMUSG00000049044

NM_001100397
NM_001282899
NM_001282900
NM_001282901
NM_007023

NM_001204165
NM_001204166
NM_001204167
NM_019688

NP_001093867
NP_001269828
NP_001269829
NP_001269830
NP_008954

NP_001191096
NP_062662

...
Wikipedia

...