R46: May cause heritable genetic damage

R-phrases (short for Risk Phrases) are defined in Annex III of European Union Directive 67/548/EEC: Nature of special risks attributed to dangerous substances and preparations. The list was consolidated and republished in Directive 2001/59/EC, where translations into other EU languages may be found.

These risk phrases are used internationally, not just in Europe, and there is an ongoing effort towards complete international harmonization.

Note: Missing R-numbers indicate phrases that have been deleted or replaced by other phrases.

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