Pyruvate dehydrogenase (lipoamide) alpha 1

PDHA1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1NI4, 2OZL, 3EXE, 3EXF, 3EXG, 3EXH, 3EXI

Identifiers

Aliases

PDHA1, PDHA, PDHCE1A, PHE1A, PDHAD, Pyruvate dehydrogenase (lipoamide) alpha 1, pyruvate dehydrogenase alpha 1, pyruvate dehydrogenase E1 alpha 1 subunit

External IDs

MGI: 97532 HomoloGene: 121491 GeneCards: PDHA1

Gene location (Human)

Chr.	X chromosome (human)

Band	Xp22.12	Start	19,343,893 bp
Band	Xp22.12	End	19,361,705 bp

Gene location (Mouse)

Chr.	X chromosome (mouse)

Band	X F4\|X 73.95 cM	Start	160,122,209 bp
Band	X F4\|X 73.95 cM	End	160,138,413 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• pyruvate dehydrogenase activity • oxidoreductase activity • pyruvate dehydrogenase (acetyl-transferring) activity • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor • pyruvate dehydrogenase (NAD+) activity • protein binding
Cellular component	• intracellular membrane-bounded organelle • myelin sheath • pyruvate dehydrogenase complex • mitochondrial matrix • nucleus • nucleolus • mitochondrion
Biological process	• mitochondrial acetyl-CoA biosynthetic process from pyruvate • tricarboxylic acid cycle • regulation of acetyl-CoA biosynthetic process from pyruvate • pyruvate metabolic process • glucose metabolic process • metabolism • oxidation-reduction process • acetyl-CoA biosynthetic process from pyruvate • cellular nitrogen compound metabolic process • carbohydrate metabolic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


5160


18597

Ensembl


ENSG00000131828


ENSMUSG00000031299

UniProt


P08559 Q5JPT9


P35486

RefSeq (mRNA)


NM_000284 NM_001173454 NM_001173455 NM_001173456


NM_008810

RefSeq (protein)


NP_000275 NP_001166925 NP_001166926 NP_001166927


NP_032836

Location (UCSC)

Chr X: 19.34 – 19.36 Mb

Chr X: 160.12 – 160.14 Mb

PubMed search

1NI4, 2OZL, 3EXE, 3EXF, 3EXG, 3EXH, 3EXI

NM_000284
NM_001173454
NM_001173455
NM_001173456

NM_008810

NP_000275
NP_001166925
NP_001166926
NP_001166927

...
Wikipedia