Prostate specific antigen

KLK3

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2ZCH, 2ZCK, 2ZCL, 3QUM

Identifiers

Aliases

KLK3, APS, KLK2A1, PSA, hK3, kallikrein related peptidase 3, Prostate Specific Antigen、 PSA

External IDs

OMIM: 176820 MGI: 97320 HomoloGene: 68141 GeneCards: KLK3

Genetically Related Diseases

prostate cancer

Gene ontology
Molecular function	• peptidase activity • serine-type peptidase activity • endopeptidase activity • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides • protein binding • hydrolase activity • serine-type endopeptidase activity
Cellular component	• extracellular exosome • nucleus • protein complex • extracellular region • extracellular space
Biological process	• negative regulation of angiogenesis • cellular protein metabolic process • antibacterial peptide production • proteolysis
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


354


18048

Ensembl


ENSG00000142515


ENSMUSG00000066513

UniProt


P07288


P00757

RefSeq (mRNA)


NM_001030047 NM_001030048 NM_001030049 NM_001030050 NM_001648


NM_010915

RefSeq (protein)


NP_001025218 NP_001025219 NP_001639


NP_035045.2 NP_035045

Location (UCSC)

Chr 19: 50.85 – 50.86 Mb

Chr 7: 44.21 – 44.21 Mb

PubMed search

2ZCH, 2ZCK, 2ZCL, 3QUM

NM_001030047
NM_001030048
NM_001030049
NM_001030050
NM_001648

NM_010915

NP_001025218
NP_001025219
NP_001639

NP_035045.2
NP_035045

...
Wikipedia