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Propylene glycol dinitrate

Propylene glycol dinitrate
PGDN.png
Names
IUPAC name
Propylene dinitrate
Other names
Propane-1,2-diyl dinitrate;
1,2-Bis(nitrooxy)propane
Identifiers
6423-43-4 N
3D model (Jmol) Interactive image
ChEMBL ChEMBL206527 YesY
ChemSpider 21472 YesY
ECHA InfoCard 100.026.527
PubChem 22933
Properties
C3H6N2O6
Molar mass 166.09 g·mol−1
Appearance colorless liquid
Odor disagreeable
Density 1.232 g/cm³ (at 20 °C)
Melting point −27.7 °C (−17.9 °F; 245.5 K)
Boiling point 121 °C (250 °F; 394 K) (decomposes below boiling point)
0.1% (20°C)
Vapor pressure 0.07 mmHg (22°C)
Hazards
Lethal dose or concentration (LD, LC):
LD50 (median dose)
930 mg kg−1 (IP, rat)
US health exposure limits (NIOSH):
PEL (Permissible)
none
REL (Recommended)
TWA 0.05 ppm (0.3 mg/m3) [skin]
IDLH (Immediate danger)
N.D.
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Propylene glycol dinitrate (PGDN, 1,2-propylene glycol dinitrate, or 1,2-propanediol dinitrate) is an organic chemical, an ester of nitric acid and propylene glycol. It is structurally similar to nitroglycerin, except that it has one fewer -O-NO2 group. It is a characteristically and unpleasantly smelling colorless liquid, which decomposes at 121 °C, below its boiling point. It is flammable and explosive. It is shock-sensitive and burns with a clean flame producing water, carbon monoxide, and nitrogen.

The principal current use of propylene glycol dinitrate is as a propellant in Otto Fuel II, together with 2-nitrodiphenylamine and dibutyl sebacate. Otto Fuel II is used in some torpedoes as a propellant.

Nitrates of polyhydric alcohols, of which propylene glycol dinitrate is an example, have been used in medicine for the treatment of angina pectoris, and as explosives since the mid-nineteenth century.

PGDN affects blood pressure, causes respiratory toxicity, damages liver and kidneys, distorts vision, causes methoglobinuria, and can cause headache and lack of coordination. It may be absorbed through skin. Its primary toxicity mechanism is methemoglobinemia. It may cause permanent nerve damage.


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