Names | |
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Preferred IUPAC name
Propanoic anhydride
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Other names
Propionic anhydride
Propanoyl propanoate |
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Identifiers | |
3D model (Jmol)
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ChemSpider | |
ECHA InfoCard | 100.004.218 |
PubChem CID
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RTECS number | UF9100000 |
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Properties | |
C6H10O3 | |
Molar mass | 130.14 g/mol |
Appearance | Clear liquid, with a strong smell similar to vinegar |
Density | 1.015 g/cm3, liquid |
Melting point | −42 °C (−44 °F; 231 K) |
Boiling point | 167 to 170 °C (333 to 338 °F; 440 to 443 K) |
Reacts to give propanoic acid | |
Viscosity | 1.144 cP at ?°C |
Hazards | |
Main hazards | flammable |
Safety data sheet | External MSDS |
R-phrases | R34 |
S-phrases | S26-45 |
Flash point | 63 °C (145 °F; 336 K) |
Related compounds | |
Related compounds
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Acetic anhydride |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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what is ?) | (|
Infobox references | |
Propanoic anhydride is an organic compound with the formula (CH3CH2CO)2O. This simple acid anhydride is a colourless liquid. It is a widely used reagent in organic synthesis.
Propanoic anhydride has been prepared by dehydration of propanoic acid using ketene:
Propanoic anhydride is strong smelling and corrosive, and will cause burns on contact with skin. Vapour can burn eyes and lungs.
Due to its potential use as a precursor in the synthesis of fentanyl and fentanyl analogs, propanoic anhydride is regulated by the United States Drug Enforcement Administration as a List I chemical under the Controlled Substances Act.