Properdin
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| Aliases | CFP, BFD, PFC, PFD, PROPERDIN, complement factor properdin, Properdin | ||||||||||||||
| External IDs | MGI: 97545 HomoloGene: 1969 GeneCards: CFP | ||||||||||||||
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| Species | Human | Mouse | |||||||||||||
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| Location (UCSC) | Chr X: 47.62 – 47.63 Mb | Chr X: 20.93 – 20.93 Mb | |||||||||||||
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Properdin or Factor P is the only known positive regulator of complement activation that stabilizes the alternative pathway convertases. It is found in the blood serum of more complex animals.
Properdin is a gamma globulin protein composed of multiple identical protein subunits with a separate ligand-binding site. Native properdin occurs in head-to-tail dimers, trimers and tetramers in the fixed ratio 22:52:28.
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Wikipedia