Prolactin

PRL

PRL structure.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1RW5, 2Q98, 3D48, 3EW3, 3MZG, 3N06, 3N0P, 3NCB, 3NCC, 3NCE, 3NCF, 3NPZ

Identifiers

PRL, GHA1, prolactin

External IDs

MGI: 97762 HomoloGene: 732 GeneCards: PRL

Genetically Related Diseases

mammary Paget's disease

Gene ontology
Molecular function	• prolactin receptor binding • protein binding • hormone activity
Cellular component	• extracellular region • secretory granule • endosome lumen
Biological process	• female pregnancy • cellular protein metabolic process • cell surface receptor signaling pathway • JAK-STAT cascade involved in growth hormone signaling pathway • lactation • cell proliferation • positive regulation of JAK-STAT cascade • regulation of multicellular organism growth • parturition • response to nutrient • circadian rhythm • positive regulation of cell proliferation • response to organic cyclic compound • regulation of ossification • response to estradiol • response to lipopolysaccharide • cellular response to hormone stimulus • multicellular organismal response to stress • response to drug • ovulation cycle • response to ethanol • positive regulation of epithelial cell proliferation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


5617


19109


ENSG00000172179


ENSMUSG00000021342


P01236


P06879

RefSeq (mRNA)


NM_000948 NM_001163558


NM_001163530 NM_011164

RefSeq (protein)


NP_000939 NP_001157030


n/a

Location (UCSC)

Chr 6: 22.29 – 22.3 Mb

Chr 13: 27.06 – 27.07 Mb

PubMed search

1RW5, 2Q98, 3D48, 3EW3, 3MZG, 3N06, 3N0P, 3NCB, 3NCC, 3NCE, 3NCF, 3NPZ

ENSG00000172179

ENSMUSG00000021342

NM_000948
NM_001163558

NM_001163530
NM_011164

NP_000939
NP_001157030

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Wikipedia

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