Programmed cell death-ligand 1

CD274

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3BIK, 3BIS, 3FN3, 3SBW, 4Z18, 4ZQK, 5C3T, 5J89, 5J8O

Identifiers

CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, CD274 molecule, Programmed cell death 1 ligand 1

External IDs

Gene ontology
Molecular function	• protein binding
Cellular component	• integral component of membrane • membrane • plasma membrane • cell surface • extracellular exosome • external side of plasma membrane • endomembrane system
Biological process	• negative regulation of interleukin-10 production • response to cytokine • negative regulation of interferon-gamma production • negative regulation of tumor necrosis factor superfamily cytokine production • positive regulation of cell migration • T cell costimulation • toxin transport • negative regulation of activated T cell proliferation • regulation of activated T cell proliferation • cell surface receptor signaling pathway • negative regulation of T cell proliferation • regulation of T cell apoptotic process • immune response • positive regulation of T cell proliferation • signal transduction • positive regulation of interleukin-10 secretion • regulation of activated CD4-positive, alpha-beta T cell apoptotic process • positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


29126


60533


ENSG00000120217


ENSMUSG00000016496


Q9NZQ7


Q9EP73

RefSeq (mRNA)


NM_001314029 NM_001267706 NM_014143


NM_021893

RefSeq (protein)


NP_001254635 NP_001300958 NP_054862


NP_068693

Location (UCSC)

PubMed search