In Ancient Greek grammar, privative a (also known as privative alpha; in Latin, α prīvātīvum, in Greek, α στερητικόν) is the prefix a- that expresses negation or absence (e.g. a-theos, ). It is derived from a Proto-Indo-European syllabic nasal *n̥-, the zero ablaut grade of the negation *ne, i.e. /n/ used as a vowel. For this reason, it usually appears as an- before vowels (e.g. an-alphabetism, an-esthesia, an-archy). It shares the same root with the Greek prefix nē or ne, in Greek νη or νε, that is also privative (e.g. ne-penthe).
The same prefix appears in Sanskrit, also as a-, an-
In Latin, the cognate prefix is in-. The prepositional prefix in- is different.
In English and other West Germanic languages, the cognate is un- (or on-).
In North Germanic languages, the -n- has disappeared and Old Norse has ú- (e.g. ú-dáins-akr), Danish and Norwegian have u-, whereas Swedish uses o- (pronounced [u]), and Icelandic and Faroese use the related .