Nepenthe /nᵻˈpɛnθiː/ (Ancient Greek: νηπενθές) is a fictional medicine for sorrow, literally an anti-depressant – a "drug of forgetfulness" mentioned in ancient Greek literature and Greek mythology, depicted as originating in Egypt.
The carnivorous plant genus Nepenthes is named after the drug nepenthe.
The word nepenthe first appears in the fourth book of Homer's Odyssey:
ἔνθ᾽ αὖτ᾽ ἄλλ᾽ ἐνόησ᾽ Ἑλένη Διὸς ἐκγεγαυῖα:
αὐτίκ᾽ ἄρ᾽ εἰς οἶνον βάλε φάρμακον, ἔνθεν ἔπινον,
νηπενθές τ᾽ ἄχολόν τε, κακῶν ἐπίληθον ἁπάντων.
Then Helen, daughter of Zeus, took other counsel.
Straightway she cast into the wine of which they were drinking a drug
to quiet all pain and strife, and bring forgetfulness of every ill.
Odyssey, Book 4, v. 219–221
Figuratively, nepenthe means "that which chases away sorrow". Literally it means 'not-sorrow' or 'anti-sorrow': νη, ne, i.e. "not" (privative prefix), and πενθές, from πένθος, penthos, i.e. "grief, sorrow, or mourning". In the Odyssey, in the passage quoted above, nepenthes pharmakon (i.e. an anti-sorrow drug) is a magical potion given to Helen by Polydamna the wife of the noble Egyptian Thon; it quells all sorrows with forgetfulness.