Princess Leopoldina of Savoy (Leopoldina Maria; 21 December 1744 – 17 April 1807) was a Princess of Savoy and later the Princess of Melfi, as wife of Giovanni Andrea VI Doria-Pamphilj-Landi, (13) Prince of Melfi. She was the older sister of the princesse de Lamballe.

Leopoldina Maria, Princess of Savoy was born at the Palazzo Carignano in Turin, the capital of the Kingdom of Sardinia. She was the third child of ten, she was her parents second daughter.

Her father Louis Victor of Savoy was the Prince of Carignano and head of the cadet branch of the House of Savoy which ruled over Sardinia. Her mother was a daughter of the Landgrave of Hesse-Rotenburg and was a sister of the late Queen Polyxena of Sardinia, wife of Charles Emmanuel III of Sardinia. As such, Charles Emmanuel's children were Leopoldina's first cousins including the future King Victor Amadeus III of Sardinia.

She received a good education and was fluent in French, Italian, and German. Her brothers included Victor Amadeus II, Prince of Carignano, grandfather of King Charles Albert of Sardinia. Her younger brother was Eugenio, Count of Villafranca, founder of the Villafranca line of the Princes of Carignano.

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