A positronic brain is a fictional technological device, originally conceived by science fiction writer Isaac Asimov. It functions as a central processing unit (CPU) for robots, and, in some unspecified way, provides them with a form of consciousness recognizable to humans. When Asimov wrote his first robot stories in 1939 and 1940, the positron was a newly discovered particle, and so the buzz word positronic added a contemporary of popular science to the concept. The short story "Runaround", by Asimov, elaborates on the concept, in the context of his fictional Three Laws of Robotics.
Asimov remained vague about the technical details of positronic brains except to assert that their substructure was formed from an alloy of platinum and iridium. They were said to be vulnerable to radiation and apparently involve a type of volatile memory (since robots in storage required a power source keeping their brains "alive"). The focus of Asimov's stories was directed more towards the software of robots—such as the Three Laws of Robotics—than the hardware in which it was implemented, although it is stated in his stories that to create a positronic brain without the Three Laws, it would have been necessary to spend years redesigning the fundamental approach towards the brain itself.
Within his stories of robotics on Earth and their development by U.S. Robots, Asimov's positronic brain is less of a plot device and more of a technological item worthy of study.
A positronic brain cannot ordinarily be built without incorporating the Three Laws; any modification thereof would drastically modify robot behavior. Behavioral dilemmas resulting from conflicting potentials set by inexperienced and/or malicious users of the robot for the Three Laws make up the bulk of Asimov's stories concerning robots. They are resolved by applying the science of logic and psychology together with mathematics, the supreme solution finder being Dr. Susan Calvin, Chief Robopsychologist of U.S. Robots.