PolyA-binding protein

PABPC1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1CVJ, 1G9L, 1JGN, 1JH4, 2K8G, 2RQG, 2RQH, 2X04, 3KTP, 3KTR, 3KUI, 3KUJ, 3KUR, 3KUS, 3KUT, 3PKN, 3PTH, 4F02, 4F25, 4F26, 5DX1, 5DXA, 5DX8, 2D9P
Identifiers
Aliases	PABPC1, PAB1, PABP, PABP1, PABPC2, PABPL1, poly(A) binding protein cytoplasmic 1
External IDs	MGI: 1349722 HomoloGene: 37638 GeneCards: PABPC1
Gene ontology Molecular function • protein binding • nucleic acid binding • protein C-terminus binding • translation activator activity • poly(U) RNA binding • poly(A) binding • mRNA 3'-UTR binding • RNA binding Cellular component • intracellular ribonucleoprotein complex • focal adhesion • catalytic step 2 spliceosome • cytoplasmic stress granule • cytoplasm • cytoplasmic ribonucleoprotein granule • spliceosomal complex • membrane • extracellular exosome • nucleus • cytosol Biological process • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • mRNA stabilization • mRNA splicing, via spliceosome • regulation of mRNA stability • RNA splicing • mRNA polyadenylation • mRNA processing • nuclear-transcribed mRNA poly(A) tail shortening • positive regulation of viral genome replication • translational initiation • negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • positive regulation of translation • gene silencing by RNA • positive regulation of nuclear-transcribed mRNA poly(A) tail shortening • positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26986	18458
Ensembl	ENSG00000070756	ENSMUSG00000022283
UniProt	P11940	P29341
RefSeq (mRNA)	NM_002568	NM_008774
RefSeq (protein)	NP_002559	NP_032800
Location (UCSC)	Chr 8: 100.69 – 100.72 Mb	Chr 15: 36.6 – 36.61 Mb
PubMed search

1CVJ, 1G9L, 1JGN, 1JH4, 2K8G, 2RQG, 2RQH, 2X04, 3KTP, 3KTR, 3KUI, 3KUJ, 3KUR, 3KUS, 3KUT, 3PKN, 3PTH, 4F02, 4F25, 4F26, 5DX1, 5DXA, 5DX8, 2D9P

26986

18458

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Wikipedia